Bibliographic Info
Recommendation
Recommended in favor
Strong
Certainty of evidence
Moderate
In inpatient settings, WHO strongly recommends using LF-LAM to assist in the diagnosis of active TB in HIV-positive adults, adolescents and children:
- with signs and symptoms of TB (pulmonary and/or
extrapulmonary) (strong recommendation, moderate certainty in the evidence about the intervention effects); or
- with advanced HIV disease; or
- who are seriously ill (strong recommendation, moderate
certainty in the evidence about the intervention effects); or
- irrespective of signs and symptoms of TB and with a CD4 cell
count <200 (strong recommendation, moderate certainty in the evidence about the intervention effects).
Also Featured In
This recommendation also appears in the following guidelines:
Lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis of active tuberculosis in people living with HIV: policy update 2019
WHO consolidated guidelines on tuberculosis: module 3: diagnosis – rapid diagnostics for tuberculosis detection: web annex 2. GRADE profiles
WHO consolidated guidelines on tuberculosis: module 3: diagnosis – rapid diagnostics for tuberculosis detection: web annex 2. GRADE profiles
WHO consolidated guidelines on tuberculosis: module 3: diagnosis – rapid diagnostics for tuberculosis detection: web annex 2. GRADE profiles
WHO consolidated guidelines on tuberculosis: module 6: tuberculosis and comorbidities.
WHO consolidated guidelines on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 3rd ed.