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Bibliographic Info

GuidelineUpdated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV
Year of Publication2018
Issuing InstitutionWHO

Recommendation

Status
Maintained

Recommended in favor

Strong

tenofovir disoproxil fumarate (TDF) + lamivudine (3TC) or emtricitabine (FTC) is recommended as the preferred backbone regimen for HIV post-exposure prophylaxis

Notes and Remarks

a Indeterminate range: a range of viral copy equivalents that would be too low to be accurately diagnosed as positive. The indeterminate range suggested is currently estimated to be approximately equivalent to a cycle threshold of 33 on the Roche COBAS® Ampliprep/COBAS® TaqMan® HIV-1 Qualitative Test v2.0 assay.

Also Featured In

This recommendation also appears in the following guidelines:

Originally Developed
Guideline

Guidelines on post-exposure prophylaxis for HIV and the use of co-trimoxazole prophylaxis for HIV-related infections among adults, adolescents and children: recommendations for a public health approach: December 2014 supplement to the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection

Year2014
InstitutionWorld Health Organization
Guideline

Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach

Year2016
InstitutionWHO
Guideline

Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach

Year2021
InstitutionWHO
Guideline

Guidelines for HIV post-exposure prophylaxis

Year2025
InstitutionWorld Health Organization
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