Bibliographic Info
GuidelineWHO Guidelines for malaria, 14 March 2023
Year of Publication2023
Issuing InstitutionWHO
Recommendation
Status
Maintained
Recommended in favor
Conditional
Certainty of evidence
Moderate
WHO suggests deploying pyrethroid-PBO nets instead of pyrethroid-only long-lasting insecticidal nets (LLINs) for the prevention and control of malaria in children and adults in areas with ongoing malaria transmission where the principal malaria vector(s) exhibit pyrethroid resistance.
Notes and Remarks
- 1.WHO recommends pyrethroid-PBO nets that have been prequalified by WHO for areas where resistance in the principal malaria vector(s) is: a) confirmed, b) of intermediate level and c) conferred (at least in part) by a monooxygenasebased resistance mechanism, as determined by standard procedures.
- 2.Pyrethroid-PBO nets combine pyrethroids and a synergist, which acts by inhibiting certain metabolic enzymes within the mosquito before they can have a toxic effect . Therefore, compared to a pyrethroid-only net, a pyrethroid-PBO net should have an increased killing effect on malaria vectors that express such resistance mechanisms.
Also Featured In
This recommendation also appears in the following guidelines:
Originally Developed
Guideline
Guidelines for Malaria Vector Control
Year2019
InstitutionWHO
Guideline
WHO guidelines for malaria, 16 February 2021.
Year2021
InstitutionWHO
Guideline
WHO guidelines for malaria, 13 July 2021.
Year2021
InstitutionWHO
Guideline
WHO guidelines for malaria, 18 February 2022.
Year2022
InstitutionWHO