Bibliographic Info
GuidelineGuidelines for the treatment of malaria
Year of Publication2015
Issuing InstitutionWorld Health Organization
Recommendation
Status
Maintained
Recommended in favor
Strong
Certainty of evidence
High
Duration of ACT treatment: ACT regimens should provide 3 days treatment with an artemisinin derivative.
Notes and Remarks
- 1)A 3-day course of the artemisinin component of ACTs covers two asexual cycles, ensuring that only a small fraction of parasites remain for clearance by the partner drug, thus reducing the potential development of resistance to the partner drug.
- 2)Shorter courses (1–2 days) are therefore not recommended, as they are less effective, have less effect on gametocytes and provide less protection for the slowly eliminated partner drug.
Also Featured In
This recommendation also appears in the following guidelines:
Originally Developed
Guideline
Guidelines for the Treatment of Malaria
Year2010
Institution
Guideline
WHO guidelines for malaria, 16 February 2021.
Year2021
InstitutionWHO
Guideline
WHO guidelines for malaria, 13 July 2021.
Year2021
InstitutionWHO
Guideline
WHO guidelines for malaria, 18 February 2022.
Year2022
InstitutionWHO
Guideline
WHO guidelines for malaria, 31 March 2022.
Year2022
InstitutionWHO
Guideline
WHO guidelines for malaria, 3 June 2022.
Year2022
InstitutionWHO
Guideline
WHO guidelines for malaria, 25 November 2022.
Year2022
InstitutionWorld Health Organization
Guideline
WHO guidelines for malaria, 16 October 2023.
Year2023
InstitutionWorld Health Organization
Guideline
WHO Guidelines for malaria, 14 March 2023
Year2023
InstitutionWHO
Guideline
WHO guidelines for malaria, 30 November 2024.
Year2024
InstitutionWHO