Bibliographic Info
Recommendation
Recommended in favor
Strong
Certainty of evidence
High
For the consolidation phase treatment of HIV infected adults, adolescents and children with cryptococcal meningitis or disseminated non-meningeal disease, the following 8-week antifungal regimen is recommended: Fluconazole 400–800mg/day after a two-week induction with amphotericin B regimen (6–12 mg/kg/day up to 400–800 mg/day if below 19 years). Fluconazole 800 mg/day after induction treatment with short-course amphotericin B or fluconazole-based induction regimen (fluconazole 12 mg/kg/day up to 800 mg/day if below 19 years)
Also Featured In
This recommendation also appears in the following guidelines:
Rapid advice : diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children