Bibliographic Info
GuidelineUpdate of the Mental Health Gap Action Programme (mhGAP) guidelines for mental, neurological and substance use disorders, 2015
Year of Publication2015
Issuing InstitutionWorld Health Organization
Recommendation
Status
Updated
Recommended in favor
Strong
Certainty of evidence
Low
(Epilepsy) When intravenous access is not available for the control of acute seizures in adults, non- parenteral routes of benzodiazepine administrations should be used. Options include rectal diazepam, buccal or intranasal midazolam, rectal or intranasal lorazepam. The preference may be guided by availability, expertise and social preference. Some benzodiazepines (lorazepam or midazolam) may be given by intramuscular route, which requires additional expertise. Intramuscular administration of diazepam is not recommended because of erratic absorption.