New Evidence Available
Updated Recommendation
A new evidence synthesis was published:2025, WHO updated recommendations on HIV clinical management: recommendations for a public health approach
View latest version (2025)Bibliographic Info
GuidelineConsolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach
Year of Publication2016
Issuing InstitutionWHO
Recommendation
Status
Retired
Recommended in favor
Strong
Certainty of evidence
Low
First-line ART for adolescents should consist of two nucleoside reverse transcriptase inhibitor (NRTI) plus an non-nucleoside reverse transcriptase inhibitor (NNRTI) or an INSTI: tenofovir disoproxil fumarate (TDF) + lamivudine (3TC ) or emtricitabine (FTC) + efavirenz (EFV) as a fixed-dose combination is recommended as the preferred option to initiate ART