Bibliographic Info
Recommendation
Recommended in favor
Strong
Certainty of evidence
High
Treat adults and children with severe malaria (including infants, pregnant women in all trimesters and lactating women) with intravenous or intramuscular artesunate for at least 24 h and until they can tolerate oral medication. Once a patient has received at least 24 h of parenteral therapy and can tolerate oral therapy, complete treatment with 3 days of artemisinin-based combination therapy (ACT).
Also Featured In
This recommendation also appears in the following guidelines:
Guidelines for the treatment of malaria
WHO guidelines for malaria, 13 July 2021.
WHO guidelines for malaria, 18 February 2022.
WHO guidelines for malaria, 31 March 2022.
WHO guidelines for malaria, 3 June 2022.
WHO guidelines for malaria, 25 November 2022.
WHO guidelines for malaria, 16 October 2023.
WHO Guidelines for malaria, 14 March 2023
WHO guidelines for malaria, 30 November 2024.
WHO guidelines for malaria, 13 August 2025