Once high coverage with one core intervention has been achieved, programmes may consider deploying the other core intervention as an approach to prevent, manage and mitigate insecticide resistance. The insecticide-treated nets (ITNs) and indoor residual spraying (IRS) products selected for co-deployment must not contain the same insecticide class(es). For instance, Indoor Residual Spraying (IRS) with a pyrethroid should not be deployed in the same households or areas as ITNs. The decision to deploy a second core vector control intervention should only be taken after conducting a prioritization analysis across malaria interventions, not just vector control, to ensure maximum impact of any additional resources