Bibliographic Info
Recommendation
Recommended in favor
Strong
Certainty of evidence
Moderate
Screening for cryptococcal antigen followed by pre-emptive antifungal therapy among cryptococcal antigen–positive people to prevent the development of invasive cryptococcal disease is recommended before initiating or reinitiating ART for adults and adolescents living with HIV who have a CD4 cell count <100 cells/mm3
Notes and Remarks
Screening for cryptococcal antigen is the optimal approach for guiding resources in a public health approach and is the preferred approach for identifying risk of progression to disease when managing people presenting with advanced HIV disease.
Also Featured In
This recommendation also appears in the following guidelines:
Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach
Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV.
WHO guidelines on the management of advanced HIV disease