In communities approaching the interruption of transmission (defined as having no autochthonous human cases reported for 5 consecutive years), WHO suggests a verification framework that consists of: 1. Testing for Schistosoma infection in humans with a diagnostic that has high sensitivity and specificity. This may require the use of a two-step diagnostic process starting with a high sensitivity test confirmed with a second, high specificity test. 2. Testing for Schistosoma infection in snails with a diagnostic that has high sensitivity and specificity. This may require the use of a two-step diagnostic process starting with a high sensitivity test confirmed with a second, high specificity test. 3. Testing for Schistosoma infection in non-human mammalian hosts, as applicable, with a diagnostic that has high sensitivity and specificity. This may require the use of a two-step diagnostic process starting with a high sensitivity test confirmed with a second, high specificity test.