Bibliographic Info
GuidelineWHO guidelines on the management of advanced HIV disease
Year of Publication2025
Issuing InstitutionWorld Health Organization
Recommendation
Status
Maintained
Recommended in favor
Strong
Certainty of evidence
Moderate
WHO recommends rapid initiation of antiretroviral therapy (ART) in people with mpox infection and HIV who are ART naïve or have had a prolonged interruption of ART
Notes and Remarks
- Early HIV testing should be conducted when patients present with suspected or confirmed mpox infection.
- The patient should be referred to appropriate services for ART initiation as soon as possible, aiming to provide therapy within 7 days of HIV diagnosis including the offer of same-day start.
- In people who are already on ART and with undetectable viral load, ART regimen should be continued without interruption or change. The viral load test result should be less than 1 year old; if not, a new viral load test should be conducted.
Also Featured In
This recommendation also appears in the following guidelines:
Originally Developed
Guideline
Clinical management and infection prevention and control for mpox: living guideline, May 2025
Year2025
InstitutionWorld Health Organization