Bibliographic Info
GuidelineUpdate of the Mental Health Gap Action Programme (mhGAP) guidelines for mental, neurological and substance use disorders, 2015
Year of Publication2015
Issuing InstitutionWorld Health Organization
Recommendation
Status
Updated
Recommended in favor
Conditional
Certainty of evidence
Low
In people with dementia and severe depression, or when psychosocial interventions prove ineffective, the use of selective serotonin reuptake inhibitors (SSRIs) (but not tricyclic antidepressants [TCAs]) may be considered. In people with dementia and mild to moderate depression, antidepressants should not be offered as a first-line treatment.