Bibliographic Info
Recommendation
Recommended in favor
Strong
Certainty of evidence
Moderate
When cryptococcal antigen screening is not available, fluconazole primary prophylaxis should be given to adults and adolescents living with HIV who have a CD4 cell count <100 cells/mm3
Notes and Remarks
Screening for cryptococcal antigen is the optimal approach for guiding resources in a public health approach and is the preferred approach for identifying risk of progression to disease when managing people presenting with advanced HIV disease.
Also Featured In
This recommendation also appears in the following guidelines:
Guidelines for the diagnosis, prevention, and management of cryptococcal disease in HIV-infected adults, adolescents and children, March 2018: supplement to the 2016 consolidated guidelines of the use of antiretroviral drugs for treating and preventing HIV infection
Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV.
WHO guidelines on the management of advanced HIV disease