New Evidence Available
Updated Recommendation
A new evidence synthesis was published:2025, WHO guidelines for malaria, 13 August 2025
View latest version (2025)Bibliographic Info
GuidelineWHO guidelines for malaria, 30 November 2024.
Year of Publication2024
Issuing InstitutionWHO
Recommendation
Status
Retired
Recommended in favor
Strong
Certainty of evidence
Low
Indoor Residual Spraying (IRS) should be deployed for the prevention and control of malaria in children and adults living in areas with ongoing malaria transmission.
Notes and Remarks
- 1.WHO recommends IRS with a product that has been prequalified by WHO for deployment in most malaria-endemic locations. DDT, which has not been prequalified, may be used for IRS if no equally effective and efficient alternative is available, and if it is used in line with the Stockholm Convention on Persistent Organic Pollutants. IRS is considered an appropriate intervention where:
- the majority of the vector population feeds and rests inside houses;
- the vectors are susceptible to the insecticide that is being deployed;
- people mainly sleep indoors at night;
- the malaria transmission pattern is such that the population can be protected by one or two rounds of IRS per year;
- the majority of structures are suitable for spraying; and
- structures are not scattered over a wide area, resulting in high transportation and other logistical costs.
Also Featured In
This recommendation also appears in the following guidelines:
Originally Developed
Guideline
WHO guidelines for malaria, 16 October 2023.
Year2023
InstitutionWorld Health Organization