Guideline

WHO meeting report of a technical expert consultation: non-inferiority analysis of Xpert MTB/RIF ultra compared to Xpert MTB/RIF

Year of Publication

2017

Issuing Institution

WHO

Links

WHO IRIS,Google Scholar

Recommendations

7 included recommendations

Xpert MTB/RIF should be used rather than conventional microscopy, culture and DST as the initial diagnostic test in adults suspected of having multidrug-resistant tuberculosis (MDR-TB) or HIV-associated TB

Status

Retired

Recommended in favor

Strong

Certainty of evidence

High

Xpert MTB/RIF should be used in preference to conventional microscopy and culture as the initial diagnostic test for cerebrospinal fluid specimens from patients suspected of having TB meningitis

Status

Retired

Recommended in favor

Strong

Certainty of evidence

Very low

Xpert MTB/RIF may be used as a replacement test for usual practice (including conventional microscopy, culture or histopathology) for testing specific non-respiratory specimens (lymph nodes and other tissues) from patients suspected of having extrapulmonary TB

Status

Retired

Recommended in favor

Conditional

Certainty of evidence

Very low

Xpert MTB/RIF should be used rather than conventional microscopy, culture and DST as the initial diagnostic test in children suspected of having multidrug-resistant tuberculosis (MDR-TB) or HIV-associated TB

Status

Retired

Recommended in favor

Strong

Certainty of evidence

Very low

Xpert MTB/RIF may be used rather than conventional microscopy and culture as the initial diagnostic test in all adults suspected of having TB

Status

Retired

Recommended in favor

Conditional

Certainty of evidence

High

Xpert MTB/RIF may be used rather than conventional microscopy and culture as the initial diagnostic test in all children suspected of having TB

Status

Retired

Recommended in favor

Conditional

Certainty of evidence

Very low

Xpert MTB/RIF may be used as a follow-on test to microscopy in adults suspected of having TB but not at risk of multidrug-resistant tuberculosis (MDR-TB) or HIV-associated TB, especially when further testing of smear negative specimens is necessary

Status

Retired

Recommended in favor

Conditional

Certainty of evidence

High