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WHO position paper on immunization to protect infants against respiratory syncytial virus disease, May 2025

Year of Publication
2025
Issuing Institution
World Health Organization
Links
WHO

Recommendations

2 included recommendations

[Immunization to protect infants against respiratory syncytial virus disease]. For countries deciding to use the maternal vaccine as the primary preventive strategy, WHO recommends administering a single dose of RSVpreF in the third trimester of pregnancy, as defined in the local context (defined as ≥28 weeks gestation in most settings)

Status
New

Recommended

Certainty of evidence

Moderate

[Immunization to protect infants against respiratory syncytial virus disease]. For countries deciding to use a long-acting monoclonal antibody as the primary preventive strategy, WHO recommends a single dose at birth, or at the earliest opportunity thereafter if year-round administration is adopted. In a seasonal approach, administration of a single dose of a long-acting monoclonal antibody is recommended for infants and should begin shortly before the start of the RSV season, as well as at birth or the earliest opportunity thereafter for infants born during the RSV season

Status
New

Recommended

Certainty of evidence

Moderate

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