Guideline

Guidance on oral pre-exposure prophylaxis (PrEP) for serodiscordant couples, men and transgender women who have sex with men at high risk of HIV: recommendations for use in the context of demonstration projects, July 2012

Year of Publication

2012

Issuing Institution

World Health Organization

Links

WHO IRIS,WHO IRIS

Recommendations

3 included recommendations

In countries where HIV transmission occurs among serodiscordant couples, where discordant couples can be identified and where additional HIV prevention choices for them are needed, daily oral PrEP (specifically tenofovir or the combination of tenofovir and emtricitabine) may be considered as a possible additional intervention for the uninfected partner

Status

Maintained

Recommended in favor

Conditional

Certainty of evidence

High

The existing recommendation to offer daily oral PrEP as an additional HIV prevention choice for the negative partner in a serodiscordant relationship remains relevant for people who inject drugs and are in a serodiscordant relationship

Status

Maintained

Recommended in favor

Conditional

Certainty of evidence

High

In countries where HIV transmission occurs among men and transgender women who have sex with men and additional HIV prevention choices for them are needed, daily oral PrEP (specifically the combination of tenofovir and emtricitabine) may be considered as a possible additional intervention

Status

Maintained

Recommended in favor

Conditional

Certainty of evidence

High